Metabolism and signalling are tightly coupled in bacteria.Combining several theoretical approaches, a core model is presented that describes transcriptional and allosteric control of glycolysis in Escherichia coli.Experimental data based on microarrays, signalling components and Wheel Spacer extracellular metabolites are used to estimate kinetic pa
Cardiac amyloidosis is a rare, debilitating, and usually fatal disease increasingly recognized in clinical practice despite patients presenting with Stickers non-specific symptoms of cardiomyopathy.The current standard of care (SoC) focuses on preventing further amyloid formation and deposition, either with anti-plasma cell dyscrasia (anti-PCD) the
Horizontal gene transfer and recombination occur across many groups of viruses and play key roles in important viral processes such as host-range expansion and immune-system avoidance.To have any predictive power regarding the ability of viruses to readily recombine, we must determine the extent to which epistasis restricts the success of recombina
The detection of tomatoes is of vital importance for enhancing production efficiency, with image recognition-based tomato detection methods being the primary approach.However, these methods face challenges such as the difficulty in extracting small targets, low straw detection accuracy, and slow processing speeds.Therefore, this paper proposes an i